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Doctoral Researcher Position (m/f/d)


Reg. Nr. 135/2020

Fristende: 25.06.2020

The Cluster of Excellence "Balance of the Microverse" of the Friedrich Schiller University Jena, Germany, combines expertise in life, material, optical and computational sciences to elevate microbiome studies from descriptive to hypothesis-driven and functional analyses. Our core mission is to elucidate fundamental principles of the interactions and functions in microbial communities in diverse habitats ranging from oceans and groundwater to plant and human hosts. We aim to identify the shared characteristics of disturbed or polluted ecosystems as well as infectious diseases on the microbiome level, and develop strategies for their remediation by targeted interventions. Our full spectrum of expertise in the physical and life sciences will be leveraged to address these important issues in natural habitats as well as synthetic arenas in a collaborative manner. The affiliated early career program of the Jena School for Microbial Communication (JSMC) offers an ambitious, structured and interdisciplinary post-graduate training based on top-level fundamental research.

 

The Cluster of Excellence Balance of the Microverse invites applications for a

Doctoral Researcher Position (m/f/d)

to conduct research in the group of Dr. Kathrin Fröhlich on the project

Adaptation of the major human pathogen Klebsiella pneumoniae
to multispecies environments

Klebsiella pneumoniae is a medically important, Gram-negative bacterium that has lately gained attention as the causative agent of a rising number of hospital- and community-acquired infections. The genomic repertoires of many individual K. pneumoniae isolates have been analyzed, however, little is known about the transcriptomic landscapes of K. pneumoniae in different environments. Specifically, gene expression control at the post-transcriptional level - hence the contribution of RNA-mediated regulation - has not been addressed in K. pneumoniae yet. This project aims to dissect the regulatory networks employed by K. pneumoniae to optimize expression of virulence determinants and to integrate itself into multispecies environments. The successful candidate will analyse the transcriptomes of different, clinically relevant strains of K. pneumoniae both when grown under standard conditions, as well as when in contact with host cells and within defined microbial communities. Applying sequencing-based technologies and microbiological as well as biochemical techniques, the candidate will explore regulatory pathways at the molecular level, and identify key components of the pathogen's responses to different environments.

We expect:

  • A Master of Science (or equivalent) in microbiology, biochemistry, or a related discipline. Candidates in the final stages of obtaining their degree are also eligible to apply.
  • Desirable methodological skills: experience in molecular biology, biochemistry and/or microbiology
  • Highly motivated individuals with an interest in joining one of the interdisciplinary research areas of the Microverse Cluster
  • The ability to work creatively and independently towards developing your own research project
  • An integrative and cooperative personality with enthusiasm for actively participating in the dynamic Microverse community
  • English communication skills, both written and spoken

We offer:

  • A highly communicative atmosphere within an energetic scientific network providing top-level research facilities
  • A comprehensive mentoring program and soft skill courses for early career researchers
  • ·Jena - City of Science: a young and lively town with a vibrant local cultural agenda

The three and a half year full-time doctoral researcher position (65% TV-L E13) will be funded through the Excellence Strategy of the German federal and state governments, the Carl Zeiss Foundation or the German Academic Exchange Service. The Friedrich Schiller University Jena is an equal opportunity employer and part-time contracts can be discussed. Disabled persons with comparable qualifications will receive preferential status.

Applications are exclusively accepted via the JSMC Online Application Portal:

https://apply.jsmc.uni-jena.de/

 


Please familiarize yourself with the currently available doctoral projects (www.microverse-cluster.de) and the application process as described in the Online Application Portal. Selected applicants will be invited to a recruitment meeting taking place in August. Awarding decisions will be announced shortly thereafter, and candidates are expected to be available to start their projects in autumn 2020.

Application deadline: 25th June 2020

Please consider our application information: http://www.uni-jena.de/stellenmarkt_hinweis.html.

Please also note the information on the collection of personal data on:

www.uni-jena.de/Universität/Stellenmarkt/Datenschutzhinweis

 

 

Bitte beachten sie die Informationen zur Erhebung personenbezogener Daten
Registriernummer
135/2020

 

Bewerbungsadresse
Friedrich-Schiller-Universität Jena

 

Ansprechpartner
Dr. Kathrin Fröhlich
E-Mail: https://apply.jsmc.uni-jena.de/

 

Fristen
Ausschreibung vom: 19.05.2020
Bewerbungsende: 25.06.2020
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